The Peter Attia Drive
#290 ‒ Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the future of aging resear...
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Feb 19 2024 2h 5m
Chapter 1 7 mins
Alex’s background in applying engineering to problems in medicineChapter 2 12 mins
A primer on human genetics, and the history and current landscape of DNA sequencingChapter 3 16 mins
The advent and evolution of liquid biopsies for early detection of cancerChapter 4 5 mins
The role of cell-free DNA in cancer detection: how incidental findings in non-invasive prenatal testing led to the development of liquid biopsiesChapter 5 4 mins
The development of a universal blood test for cancer detection and a discussion of specificity of testsChapter 6 7 mins
Advancements in cell-free DNA analysis and development of a multi-cancer screening test at GRAILChapter 7 4 mins
DNA methylation explainedChapter 8 5 mins
Optimizing cancer detection with methylation analysis of cfDNA in small blood samplesChapter 9 12 mins
The importance of understanding sensitivity, specificity, positive predictive value, and negative predictive value in cancer screeningChapter 10 6 mins
The performance of the GRAIL Galleri test and its ability to detect various types and stages of cancerChapter 11 11 mins
Do early cancer detection methods, like liquid biopsies, translate to improvement in overall survival?Chapter 12 5 mins
The role of epigenetics in agingChapter 13 6 mins
How cell-free DNA methylation patterns can help identify a cancer’s tissue of originChapter 14 13 mins
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