The Peter Attia Drive
#279 - AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and t...
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Nov 13 2023 27m
Chapter 1 2 mins
Pharmacologic tools for improving metabolic health, and the relationship between statins and insulin resistanceChapter 2 5 mins
SGLT-2 inhibitors: how they work and help to manage type 2 diabetesChapter 3 4 mins
The history of SGLT2 inhibitors from discovery to the current stateChapter 4 5 mins
Comparing the various FDA-approved SGLT2 inhibitorsChapter 5 2 mins
Other beneficial effects of SGLT2 inhibitors outside of glycemic controlChapter 6 8 mins
Exploring SGLT2 inhibitors as potential geroprotective moleculesChapter 7 5 mins
The side effects and risks associated with SGLT2 inhibitorsChapter 8 6 mins
Medications, lifestyle interventions, and other considerations for treating diabetes and improving metabolic healthChapter 9 5 mins
Metformin as a tool for pre-diabetics, and how metformin compares to lifestyle interventionsChapter 10 3 mins
How GLP-1 agonists compare to metformin and SGLT2 inhibitors in terms of glycemic control and weight lossChapter 11 11 mins
Exploring the relationship between statin use and the risk of developing insulin resistance and type 2 diabetesChapter 12 7 mins
Possible mechanisms of statin-induced insulin resistance and diabetes, and potential mitigation strategiesChapter 13 3 mins
How to monitor for adverse effects of statin use and assess the need for adjustmentsChapter 14 5 mins
Weighing the benefits and risks of statin use: does the diabetes risk outweigh the benefits of lowering apoB with a statin?Chapter 15
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